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US trends, ventilation and low cost vaccine

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United States

Population, 328 million

Cases, + 161,398 + 164,495 = 11,465,722

Deaths, 249,670 (0.076%)

Mississippi

https://rt.live

Rt = 0.9

Cases, + 1,395 = 138,791

UP 53% in past 14 days

Deaths, + 18 = 3,691

Up 11% in past 14 days

Hospitalizations on 19 November = 926

Up 24% in past 14 days

https://www.nytimes.com/interactive/2020/us/mississippi-coronavirus-cases.html

States

https://covid.cdc.gov/covid-data-tracker/#cases_casesper100klast7days

Trends

https://covid.cdc.gov/covid-data-tracker/#trends_dailytrendscases

Official US hospitalizations

https://gis.cdc.gov/grasp/COVIDNet/COVID19_3.html

Thursday, 26 November 2020

https://www.cdc.gov/coronavirus/2019-ncov/daily-life-coping/holidays/thanksgiving.html

Multisystem Inflammatory Syndrome in Children (MIS-C)

https://www.cdc.gov/mis-c/cases/index.html

Cases, 1,163

98% tested positive

2% has had reported contacts

Most cases develop with a 2 to 4 week delay

Male 56%

0ne to 14 years, average 8 years

Cases in Hispanics or Latinos, 412

Cases in Black, Non-Hispanic, 396

Deaths, 20

Hands Face Space and Ventilate

https://edition.cnn.com/2020/11/19/us/gym-ventilation-covid-trnd/index.html

Blacksburg, Virginia

Civil and environmental engineer

Ten feet pace (6 recommended)

Ventilation

More air flow than recommended by American Society of Heating, Refrigerating and Air-Conditioning Engineers

We don't see outbreaks above a certain threshold

And the gym with the open doors was way above that

Carbon dioxide monitor to track indoor levels

Tape on the floor to mark areas

No wandering around the gym

No partner workouts

Ventilation redesign

A gym trainer exposed 50

No one else got sick

Some decided to get tested, all tested negative

Followed up for 2 weeks

Oxford vaccine phase 2 publications

Easy to store

£3 per dose

UK way out, 100 million doses

https://covid19vaccinetrial.co.uk/phase-ii-trial-publication

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32466-1/fulltext

Late-stage clinical trials, UK, US, Brazil, South Africa, Japan, Russia

50,000 participants globally

When????

https://www.bbc.co.uk/news/health-54993652

Prof Andrew Pollard, (Study lead from Oxford)

absolutely delighted with the results

we're seeing the immune responses look exactly the same, even in those who are over 70 years of age

Levels of efficacy

Neutralising antibodies

T cells

not there yet

Data release probably, before Christmas

No competition with other vaccines

Multiple vaccines needed, We will need all of them to protect people around the globe

Russia

https://www.dw.com/en/coronavirus-digest-russia-africa-surpass-2-million-cases/a-55658580

Cases, + 23,610

United States, India, Brazil, France, Russia

Deaths, + 463 = 34,850

Moscow is the worst hit area

WHO

Europe, one death every 17 seconds (WHO)

Surge in cases, Europe and the Americas

Countries, case finding, care and isolation, cluster investigations, adequate testing with rapid results, contact tracing and supported quarantine, are facing much less disruption.

Those countries that are letting the virus run unchecked are playing with fire

Further needless deaths and suffering

A significant number of people experiencing long-term effects of the virus

Mental health pressures

Act fast, act now, act decisively

Health being seen as an investment rather than a cost

A new collective way forward is needed

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